Efficacy and Safety of Topiramate for the Treatment of Chronic Migraine
Talk about a difference in perception!!! The authors conclude that “Topiramate is safe and generally well tolerated in this group of subjects with chronic migraine, a burdensome condition with important unmet treatment needs. Safety and tolerability of topiramate were consistent with experience in previous clinical trials involving the drug.”
Look at the data and tell me is “generally” means 10% of the study population stopped due to side effects. And all of this for a whopping 1.5/91 days decrease in headache over placebo. So, we’re going to spend, what, say $600 for 3 months Topamax to have 1.5 days less HA? But let’s cut chiro Rx to save money.