Chronic migraine relief
Efficacy of coenzyme Q10 in migraine prophylaxis
Almost a 50% response with taking 300 mg CoQ10 per day. Not too shabby. This is yet another notch in the “mitochondrial dysfunction leads to neurodegenerative disorders” belt.
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Congenital heart defects and maternal biomarkers of oxidative stress
Wow. Practically by the week we are finding more and more studies linking interuterine environment and risk of chronic diseases later in the newborn’s life.
[Read more…] about Oxidative Stress Increases Number Of Heart Defects
In my book, Migraines and Epilepsy, I review the evidence that shows that oxidative stress plays a huge role in seizures. Because of this, antioxidants are a requirement in natural remedies for seizures.
[Read more…] about Natural Remedies for Seizures: Antioxidant Protection
CoQ10 Deficiency and Response to Supplementation in Pediatric and Adolescent Migraine
Given that we have shifted our thinking of the cause of migraines to a mitochondrial dysfunction / oxidative stress model, the results of this study should come as no surprise. I still find it very bothersome, though, that we have so many patients being treated for migraines under a “pain control only” model without any thought to fixing the underlying mechanism.
The problem here is that oxidative stress leads to so many other chronic diseases that the patient and doctor just missed an opportunity to change the health trajectory away from one of chronic disease.
Migraine and coronary heart disease mortality: a prospective cohort study
The bottom line is that migraine is a systemic disorder, most likely a result of altered mitochondrial function and / or oxidative stress. These dysfunctions are not limited to the brain, but rather have an effect everywhere in the body, playing a role in most, if not all, chronic diseases.
So, if this is the case, then finding increases in other diseases like heart disease should be no big surprise. So, the ONLY best way to approach migraine treatment is to look at the entire patient and make global lifestyle changes to improve the way their neurons are functioning.