Amitriptyline Effective Prophylaxis for Headache in Childhood

There are two interesting things in this article. First, headaches in children are becoming prevalent enough to warrant research studies on eliminating them. We must ask ourselves why children are now more likely to suffer from headaches. The second issue is the long term introduction and use of pharmaceutical drugs in children. Our younger generation is being raised to believe that taken drugs for our “health” is okay. I’ve seen many children in my office with complaints of headache that resolve very quickly without the need for medications.

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Factors Affecting Migraine Prophylaxis

Combination of Riboflavin, Magnesium, and Feverfew for Migraine Prophylaxis

Talk about an unexpected result! This trial used 25 mg riboflavin as a placebo, and, when all the data was in, both placebo and active arm experienced similar, positive effect. Remember that riboflavin is a part of flavin adenine dinucleotide (FAD) which participates in the formation of ATP through the electron transport chain. Recall from previous Updates that I feel we are moving towards an oxidative stress etiology for migraines. The benefit of riboflavin on migraine once again goes into the evidence pool suggesting that poor mitochondrial function leading to oxidative stress is a main contributing factor to onset of migraines.

A Combination of Riboflavin, Magnesium, and Feverfew for Migraine Prophylaxis: A Randomized Trial – Headache, Vol 10, Issue 1, Pages 33-34 –

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